MonoCore™ Protein A
Affinity capture for IgG and Fc-bearing formats. Compatible with NaOH cleaning-in-place — concentrations and contact times are listed on the datasheet.
MonoCore™ Protein A is a modified cellulose monolith with a 15 µm standard channel size, supplied as pre-assembled 1.8 mL and 5.4 mL capsules with UNF 10/32 ports. Larger formats are available on request, and the capsule connects directly to a standard FPLC system.
- Chemistry
- Protein A
- Matrix
- Modified cellulose
- Format
- 1.8 mL · 5.4 mL · larger on request
- Channel size
- 15 µm — alternative sizes on request
- Connectors
- Standard FPLC (UNF 10/32)
Detailed performance data are available on request.
- AEX
MonoCore™ Q
Strong and weak anion exchange in monolith format — for capture and impurity removal in AAV polishing, pDNA capture, and host-cell-protein clearance. Resolution that lets you use it for capture, not only polishing.
- CEX
MonoCore™ S
Strong and weak cation exchange in monolith format — for mAb and bispecific polishing. Resin-class peak resolution at membrane-class throughput.
- HIC
MonoCore™ HIC
Hydrophobic interaction in monolith format — available with Butyl or Phenyl ligands. Frequently used for aggregate removal, with tight aggregate–monomer separation at process flow rates.